Stranges Grocery in Grand Junction is significant in the areas of Commerce and Ethnic Heritage.  The store is representative of the strong commercial center that helped establish Little Italy and kept it viable.  Out of the four grocery stores that were located within the boundaries of Little Italy, Stranges is the only building that retains integrity.  The Grand Valley experienced an influx of Italian immigrants around the turn of the twentieth century.  Due to social pressure and discrimination as well as a desire for familiar cultural traditions the immigrants created

Constructed between 1912 and 1921, Serpents Trail provided the only automobile access to Colorado National Monument until 1937 when the Fruita Canyon portion of Rim Rock Drive opened.  Serpents Trail reflects engineering techniques used in the construction of early automobile roads in difficult terrain and was specifically designed to optimize the scenery of the park.

Significant for its association with the Civilian Conservation Corps and Works Progress Administration, the district includes four good examples of National Park Service Rustic style architecture.  The structures were constructed of locally quarried sandstone by the CCC with Emergency Conservation Works funding. 

Built by the Civilian Conservation Corps in 1937, to accommodate the recreational needs of visitors to Colorado National Monument, the station is significant for its association with CCC and WPA relief programs during the Great Depression. 

Built by the Civilian Conservation Corps in 1935 and 1936, as the first permanent buildings in Colorado National Monument, the caretaker’s house and garage are significant for their association with public relief projects of the Great Depression.

Constructed between 1931 and 1950, the district is significant for its role in the development of automobile access and tourism in Colorado National Monument and its contribution to the local economy during the Great Depression.  The district’s contributing features are representative of National Park Service Rustic style architecture in their use of native building materials. 

The district is the most intact historic residential area in the community and includes noted architect Eugene Groves’ 1925 Lowell School.  Developed between the 1890s and 1930s, a variety of architectural styles including Queen Anne, Colonial Revival, and Mission are represented. 

A rare local example of a vernacular Victorian commercial block, the circa 1905-1906 building symbolizes Grand Junction’s transition from a frontier town to a stable, small city.

The hotel was important to the commercial development of Grand Junction.  It served as a headquarters for traveling salesmen, a stopover for railroad tourists, and a center for local social life. 

Built in 1892 to serve the need for an African American church in Grand Junction, the Handy Chapel has been a source of spiritual and physical comfort to the resident black community and travelers in distress.